COQ9

Across TCGA pan-cancer cohorts, COQ9 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated COQ9 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher COQ9 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated COQ9 expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, PDAC, and LSCC are the cancer types where COQ9 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.910	.011	72	view →
PDAC	OS	Tertile	All	0.948	0.775	.005	20	view →
LSCC	DFS	Median	II,III,IV	0.485	1.000	.006	6	view →
UCEC	OS	Quartile	II,III,IV	0.371	1.000	.032	4	view →
CCRCC	DFS	Median	II,III,IV	0.956	0.788	.021	4	view →
GBM	DFS	Quartile	All	0.818	0.600	.035	2	view →
LUAD	OS	Tertile	All	1.000	0.792	.039	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

COQ9–COAD (DFS)

Open the COAD breakdown →