COQ8B

Across TCGA patient cohorts, COQ8B protein abundance is significantly associated with the RNA expression of many other genes, with 9,502 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible COQ8B-associated genes across cancer lineages are JCAD, ADGRA2, and TIMP3. Each is linked with COQ8B in more than 3 cancer types. Because this analysis shows association rather than direction, both COQ8B-to-partner and partner-to-COQ8B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COQ8B versus JCAD in BRCA, with a Pearson correlation of -0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COQ8B→partner) and Y-score (partner→COQ8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	JCAD →	-0.700	-0.305	<.001	.002	3	4
UCEC	ADGRA2 →	-0.707	-0.234	.006	.001	3	4
CCRCC	TIMP3 →	-1.104	-0.338	<.001	<.001	3	3
CCRCC	ZNF423 →	-0.436	-0.228	.001	.002	3	3
HNSC	MIER2 →	-0.603	-0.223	.002	.006	3	3
LUAD	RECK →	-0.511	-0.266	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,502 associations by consensus.

COQ8B vs JCAD — BRCA

Explore this scatter interactively →