COQ8A

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, COQ8A RNA expression is significantly associated with the protein abundance of many other proteins, with 10,515 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible COQ8A-associated proteins across cancer lineages are RPRD2, LUC7L3, and USF1. Each is linked with COQ8A in more than 5 cancer types. Because this analysis shows association rather than direction, both COQ8A-to-partner and partner-to-COQ8A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COQ8A versus RPRD2 in LUAD, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COQ8A→partner) and Y-score (partner→COQ8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADRPRD2 →+0.265+0.234<.001.00136
LSCCLUC7L3 →+0.207+0.216<.001<.00136
BRCAUSF1 →+0.286+0.291.001<.00135
BRCACOQ7 →+0.408+0.256<.001<.00135
UCECDIDO1 →+0.221+0.272<.001<.00135
UCECHNRNPU →+0.218+0.306<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,515 associations by consensus.

COQ8A vs RPRD2 — LUAD

Per-sample scatter of COQ8A vs RPRD2 in LUAD (Pearson r = 0.32).

Explore this scatter interactively →

Exploration