COQ8A

Across TCGA patient cohorts, COQ8A protein abundance is significantly associated with the RNA expression of many other genes, with 12,895 significant associations in total. COAD shows the largest number of these associations.

The most reproducible COQ8A-associated genes across cancer lineages are TNFAIP6, CMTM3, and PHLDA2. Each is linked with COQ8A in more than 6 cancer types. Because this analysis shows association rather than direction, both COQ8A-to-partner and partner-to-COQ8A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COQ8A versus TNFAIP6 in COAD, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COQ8A→partner) and Y-score (partner→COQ8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TNFAIP6 →	-1.063	-0.398	.001	<.001	3	7
OV	CMTM3 →	-0.776	-0.557	<.001	<.001	3	6
BRCA	PHLDA2 →	-1.376	-0.496	<.001	<.001	3	6
UCEC	ANXA2 →	-1.001	-0.322	<.001	.002	3	6
LSCC	PTHLH →	-1.638	-0.278	.002	.001	3	6
OV	PDGFRL →	-0.934	-0.448	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,895 associations by consensus.

COQ8A vs TNFAIP6 — COAD

Explore this scatter interactively →