COQ7

Across TCGA pan-cancer cohorts, COQ7 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated COQ7 data layer compared with 20 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher COQ7 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated COQ7 expression acts as an unfavorable survival marker, although some lineages such as PDAC and GBM show a favorable association.

PDAC, UCEC, and GBM are the cancer types where COQ7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	III,IV	0.584	0.295	.007	30	view →
UCEC	OS	Median	III,IV	0.449	1.000	.010	18	view →
GBM	OS	Quartile	All	0.839	0.379	.005	10	view →
LSCC	DFS	Median	All	0.824	0.631	.032	5	view →
CCRCC	DFS	Median	III,IV	1.000	0.451	.032	3	view →
LUAD	OS	Median	II,III,IV	0.899	0.446	.018	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

COQ7–PDAC (OS)

Open the PDAC breakdown →