COQ7

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, COQ7 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COQ7-associated genes across cancer lineages are CD8+ T-cells and CD8+ Tcm. Each is linked with COQ7 in more than 1 cancer types. Because this analysis shows association rather than direction, both COQ7-to-partner and partner-to-COQ7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by COQ7-low versus COQ7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COQ7→partner) and Y-score (partner→COQ7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCD8+ T-cells →+0.015+2.622.022.02231
UCECCD8+ Tcm →+0.027+2.713.011.01831
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD8+ T-cells by COQ7 expression — UCEC

Box plot of CD8+ T-cells in COQ7-low vs COQ7-high samples in UCEC.

Explore this box plot interactively →

Exploration