COQ5

Across TCGA pan-cancer cohorts, COQ5 mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated COQ5 data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher COQ5 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated COQ5 expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, PDAC, and UCEC are the cancer types where COQ5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.912	.013	42	view →
PDAC	OS	Median	All	0.915	0.777	.002	39	view →
UCEC	OS	Tertile	II,III,IV	0.312	1.000	.002	28	view →
HNSC	DFS	Tertile	II,III,IV	0.893	1.000	.005	21	view →
OV	DFS	Tertile	All	1.000	0.612	.038	8	view →
LSCC	OS	Quartile	II,III,IV	0.933	0.587	.019	8	view →
LUAD	OS	Median	II,III,IV	0.899	0.446	.018	3	view →
GBM	DFS	Tertile	All	0.846	0.592	.028	3	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

COQ5–COAD (DFS)

Open the COAD breakdown →