COQ5

Across TCGA patient cohorts, COQ5 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,759 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COQ5-associated proteins across cancer lineages are RFC2, RSRC2, and C12orf43. Each is linked with COQ5 in more than 4 cancer types. Because this analysis shows association rather than direction, both COQ5-to-partner and partner-to-COQ5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COQ5 versus RFC2 in LSCC, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COQ5→partner) and Y-score (partner→COQ5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RFC2 →	+0.403	+0.524	<.001	<.001	3	5
LSCC	RSRC2 →	+0.254	+0.414	<.001	<.001	3	5
OV	C12orf43 →	+0.468	+0.574	<.001	.003	3	5
OV	MTREX →	+0.224	+0.454	<.001	<.001	3	5
LSCC	ZNF638 →	+0.274	+0.483	<.001	<.001	3	5
GBM	SPAG7 →	+0.268	+0.186	.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,759 associations by consensus.

COQ5 vs RFC2 — LSCC

Explore this scatter interactively →