COQ5

Across TCGA cell cohorts, COQ5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,783 significant associations in total. BONE shows the largest number of these associations.

The most reproducible COQ5-associated GO terms across cancer lineages are IRES-dependent viral translational initiation, Lipoprotein localization, and Nucleoside triphosphate biosynthetic process. Each is linked with COQ5 in more than 7 cancer types. Because this analysis shows association rather than direction, both COQ5-to-partner and partner-to-COQ5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IRES-dependent viral translational initiation grouped by COQ5-low versus COQ5-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COQ5→partner) and Y-score (partner→COQ5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	IRES-dependent viral translational initiation →	+0.088	+0.619	<.001	<.001	3	8
BONE	Lipoprotein localization →	+0.157	+0.715	.001	.001	3	8
UPPER_AERODIGESTIVE_TRACT	Nucleoside triphosphate biosynthetic process →	+0.061	+0.463	<.001	.003	3	7
BONE	Regulation of fibrinolysis →	-0.481	-1.009	<.001	<.001	3	7
BONE	Regulation of wound healing →	-0.120	-0.613	<.001	.004	3	7
BLOOD_Myeloma	Golgi organization →	+0.042	+0.610	<.001	.006	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,783 associations by consensus.

IRES-dependent viral translational initiation by COQ5 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →