COQ2

Across TCGA patient cohorts, COQ2 protein abundance is significantly associated with the RNA expression of many other genes, with 501 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible COQ2-associated genes across cancer lineages are LGALS2, XBP1, and POLDIP3. Each is linked with COQ2 in more than 1 cancer types. Because this analysis shows association rather than direction, both COQ2-to-partner and partner-to-COQ2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COQ2 versus LGALS2 in LUAD, with a Pearson correlation of -0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COQ2→partner) and Y-score (partner→COQ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LGALS2 →	-1.313	-0.436	.004	.006	3	1
LUAD	XBP1 →	+1.024	+0.348	.007	.004	3	1
LUAD	POLDIP3 →	-0.589	-0.333	.004	.008	3	1
LUAD	PABPC1L →	-1.175	-0.349	<.001	.004	3	1
LUAD	PARP4 →	-0.620	-0.335	.002	.007	3	1
LUAD	TRMT1 →	-0.875	-0.349	.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 501 associations by consensus.

COQ2 vs LGALS2 — LUAD

Explore this scatter interactively →