COQ2

Across TCGA patient cohorts, COQ2 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COQ2-associated genes across cancer lineages are Mesangial cells, CD8+ naive T-cells, and Endothelial cells. Each is linked with COQ2 in more than 1 cancer types. Because this analysis shows association rather than direction, both COQ2-to-partner and partner-to-COQ2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mesangial cells grouped by COQ2-low versus COQ2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COQ2→partner) and Y-score (partner→COQ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Mesangial cells →	-0.048	-2.989	.031	.037	3	1
UCEC	CD8+ naive T-cells →	+0.058	+3.042	<.001	.018	1	1
UCEC	Endothelial cells →	-0.044	-2.957	.046	.037	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Mesangial cells by COQ2 expression — UCEC

Explore this box plot interactively →