COQ2

Across TCGA cell cohorts, COQ2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,043 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible COQ2-associated GO terms across cancer lineages are DAMP biosynthetic process, Purine deoxyribonucleoside monophosphate biosynthetic process, and Depurination. Each is linked with COQ2 in more than 11 cancer types. Because this analysis shows association rather than direction, both COQ2-to-partner and partner-to-COQ2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DAMP biosynthetic process grouped by COQ2-low versus COQ2-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COQ2→partner) and Y-score (partner→COQ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	DAMP biosynthetic process →	+0.155	+0.946	.004	.004	2	12
BLOOD_Myeloma	Purine deoxyribonucleoside monophosphate biosynthetic process →	+0.155	+0.946	.004	.004	2	12
CNS	Depurination →	+0.090	+0.507	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	DNA strand resection involved in replication fork processing →	+0.107	+0.707	.003	.007	3	8
KIDNEY	Response to nitric oxide →	+0.108	+0.770	.001	.001	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of metaphase/anaphase transition of cell cycle →	+0.118	+0.866	.002	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,043 associations by consensus.

DAMP biosynthetic process by COQ2 expression — BLOOD_Myeloma

Explore this box plot interactively →