COQ10A

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, COQ10A Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated COQ10A data layer compared with 24 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher COQ10A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated COQ10A expression acts as an unfavorable survival marker.

COAD are the cancer types where COQ10A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADOSMedianAll0.1130.806<.0016view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

COQ10A–COAD (OS)

Kaplan–Meier survival curve for COQ10A mutant vs wild-type samples in COAD.

Open the COAD breakdown →

Exploration