COQ10A

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, COQ10A RNA expression is significantly associated with the protein abundance of many other proteins, with 13,285 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COQ10A-associated proteins across cancer lineages are RFX5, POGZ, and RAD21. Each is linked with COQ10A in more than 5 cancer types. Because this analysis shows association rather than direction, both COQ10A-to-partner and partner-to-COQ10A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COQ10A versus RFX5 in HNSC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COQ10A→partner) and Y-score (partner→COQ10A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCRFX5 →+0.326+0.415<.001<.00136
LSCCPOGZ →+0.355+0.491<.001<.00135
GBMRAD21 →+0.345+0.379<.001.00835
OVS100A14 →-1.141-0.644.005<.00135
HNSCCASP4 →-0.451-0.540.003<.00135
GBMHTATIP2 →-0.554-0.395<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,285 associations by consensus.

COQ10A vs RFX5 — HNSC

Per-sample scatter of COQ10A vs RFX5 in HNSC (Pearson r = 0.33).

Explore this scatter interactively →

Exploration