COQ10A

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, COQ10A mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COQ10A-associated genes across cancer lineages are Erythrocytes and Neutrophils. Each is linked with COQ10A in more than 1 cancer types. Because this analysis shows association rather than direction, both COQ10A-to-partner and partner-to-COQ10A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Erythrocytes grouped by COQ10A-low versus COQ10A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COQ10A→partner) and Y-score (partner→COQ10A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECErythrocytes →+0.031+2.584.007.01131
UCECNeutrophils →+0.020+1.751<.001.02731
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Erythrocytes by COQ10A expression — UCEC

Box plot of Erythrocytes in COQ10A-low vs COQ10A-high samples in UCEC.

Explore this box plot interactively →

Exploration