COPZ2

Across TCGA cell cohorts, COPZ2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,225 significant associations in total. BONE shows the largest number of these associations.

The most reproducible COPZ2-associated GO terms across cancer lineages are Positive regulation of plasma membrane repair, Regulation of intracellular transport, and Response to acid chemical. Each is linked with COPZ2 in more than 12 cancer types. Because this analysis shows association rather than direction, both COPZ2-to-partner and partner-to-COPZ2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of plasma membrane repair grouped by COPZ2-low versus COPZ2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COPZ2→partner) and Y-score (partner→COPZ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of plasma membrane repair →	+0.355	+3.869	<.001	<.001	3	13
OVARY	Regulation of intracellular transport →	+0.076	+2.236	<.001	<.001	3	12
OVARY	Response to acid chemical →	+0.099	+2.505	<.001	<.001	3	12
OESOPHAGUS	Protein folding →	+0.083	+2.414	.001	<.001	3	11
LIVER	Positive regulation of extracellular matrix organization →	+0.139	+2.397	<.001	<.001	3	11
BONE	Viral life cycle →	+0.095	+3.902	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,225 associations by consensus.

Positive regulation of plasma membrane repair by COPZ2 expression — BONE

Explore this box plot interactively →