COPZ1

Across TCGA patient cohorts, COPZ1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,464 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COPZ1-associated genes across cancer lineages are SMIM10L2B, ZC3H8, and PRPF39. Each is linked with COPZ1 in more than 5 cancer types. Because this analysis shows association rather than direction, both COPZ1-to-partner and partner-to-COPZ1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COPZ1 versus SMIM10L2B in LSCC, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COPZ1→partner) and Y-score (partner→COPZ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SMIM10L2B →	-0.647	-0.287	<.001	<.001	3	6
LSCC	ZC3H8 →	-0.458	-0.188	<.001	<.001	3	5
HNSC	PRPF39 →	-0.658	-0.221	.001	<.001	3	5
HNSC	INO80 →	-0.436	-0.194	.007	.001	3	5
COAD	INPP5E →	-0.613	-0.222	.001	.007	3	5
COAD	PPP1R14A →	-0.815	-0.205	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,464 associations by consensus.

COPZ1 vs SMIM10L2B — LSCC

Explore this scatter interactively →