COPZ1

Across TCGA cell cohorts, COPZ1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,873 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible COPZ1-associated GO terms across cancer lineages are Protein linear polyubiquitination, Skin epidermis development, and Regulation of protein export from nucleus. Each is linked with COPZ1 in more than 7 cancer types. Because this analysis shows association rather than direction, both COPZ1-to-partner and partner-to-COPZ1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein linear polyubiquitination grouped by COPZ1-low versus COPZ1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COPZ1→partner) and Y-score (partner→COPZ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein linear polyubiquitination →	-0.156	-0.821	<.001	<.001	3	8
BREAST	Skin epidermis development →	-0.126	-0.484	<.001	.002	3	7
BREAST	Regulation of protein export from nucleus →	-0.069	-0.446	.008	.006	2	8
BLOOD_Lymphoma	Transport along microtubule →	+0.032	+0.812	.001	<.001	3	7
CNS	Regulation of protein refolding →	-0.070	-0.520	<.001	.001	3	6
UPPER_AERODIGESTIVE_TRACT	Deadenylation-dependent decapping of nuclear-transcribed mRNA →	+0.069	+0.633	.006	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,873 associations by consensus.

Protein linear polyubiquitination by COPZ1 expression — PANCREAS

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