COPS9

Across TCGA patient cohorts, COPS9 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,675 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COPS9-associated proteins across cancer lineages are CUL3, DTYMK, and DENND1C_S596. Each is linked with COPS9 in more than 3 cancer types. Because this analysis shows association rather than direction, both COPS9-to-partner and partner-to-COPS9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COPS9 versus CUL3 in OV, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COPS9→partner) and Y-score (partner→COPS9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CUL3 →	+0.360	+0.926	<.001	<.001	3	4
LUAD	DTYMK →	+0.327	+0.395	.001	<.001	3	4
LSCC	DENND1C_S596 →	-0.557	-0.308	<.001	<.001	3	4
LSCC	DIS3L2 →	+0.184	+0.425	<.001	<.001	3	4
LSCC	ARHGAP25_S512 →	-0.628	-0.481	.001	<.001	3	3
OV	ATG4B →	+0.498	+0.799	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,675 associations by consensus.

COPS9 vs CUL3 — OV

Explore this scatter interactively →