COPS7A

Across TCGA patient cohorts, COPS7A protein abundance is significantly associated with the RNA expression of many other genes, with 16,318 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible COPS7A-associated genes across cancer lineages are FAM111B, PTMA, and KIF2C. Each is linked with COPS7A in more than 5 cancer types. Because this analysis shows association rather than direction, both COPS7A-to-partner and partner-to-COPS7A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COPS7A versus FAM111B in LUAD, with a Pearson correlation of -0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COPS7A→partner) and Y-score (partner→COPS7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FAM111B →	-0.782	-0.149	<.001	.007	3	6
OV	PTMA →	-0.691	-0.342	<.001	<.001	3	5
BRCA	KIF2C →	-1.247	-0.326	<.001	<.001	3	5
CCRCC	MYL3 →	+1.100	+0.157	<.001	.004	3	5
BRCA	MYBL2 →	-1.716	-0.334	<.001	<.001	3	5
BRCA	CDC20 →	-1.412	-0.302	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,318 associations by consensus.

COPS7A vs FAM111B — LUAD

Explore this scatter interactively →