COPS7A

Across TCGA cell cohorts, COPS7A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,836 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible COPS7A-associated GO terms across cancer lineages are Mitotic centrosome separation, Endosomal transport, and Retrograde transport, endosome to Golgi. Each is linked with COPS7A in more than 10 cancer types. Because this analysis shows association rather than direction, both COPS7A-to-partner and partner-to-COPS7A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic centrosome separation grouped by COPS7A-low versus COPS7A-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COPS7A→partner) and Y-score (partner→COPS7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Mitotic centrosome separation →	+0.111	+0.667	<.001	<.001	3	11
SKIN	Endosomal transport →	+0.044	+0.432	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Retrograde transport, endosome to Golgi →	+0.064	+0.790	<.001	<.001	3	10
SOFT_TISSUE	Protein import into peroxisome membrane →	+0.105	+0.728	<.001	<.001	3	10
SKIN	Lysosome organization →	+0.053	+0.484	<.001	<.001	3	9
SKIN	Lytic vacuole organization →	+0.053	+0.484	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,836 associations by consensus.

Mitotic centrosome separation by COPS7A expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →