COPS6

Across TCGA patient cohorts, COPS6 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,008 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COPS6-associated proteins across cancer lineages are MEPCE, EIF4H, and BAIAP2L1. Each is linked with COPS6 in more than 7 cancer types. Because this analysis shows association rather than direction, both COPS6-to-partner and partner-to-COPS6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COPS6 versus MEPCE in LSCC, with a Pearson correlation of 0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COPS6→partner) and Y-score (partner→COPS6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MEPCE →	+0.371	+0.699	<.001	<.001	3	8
COAD	EIF4H →	+0.300	+0.440	<.001	<.001	3	7
HNSC	BAIAP2L1 →	+0.532	+0.857	<.001	.001	3	6
COAD	CASP2 →	+0.504	+0.456	<.001	<.001	3	6
LSCC	LRWD1 →	+0.347	+0.511	<.001	<.001	3	6
LSCC	POLR2H →	+0.336	+0.398	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,008 associations by consensus.

COPS6 vs MEPCE — LSCC

Explore this scatter interactively →