COPS2

Across TCGA cell cohorts, COPS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,221 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible COPS2-associated GO terms across cancer lineages are Protein localization to kinetochore, Circadian sleep/wake cycle, and Protein localization to condensed chromosome. Each is linked with COPS2 in more than 15 cancer types. Because this analysis shows association rather than direction, both COPS2-to-partner and partner-to-COPS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to kinetochore grouped by COPS2-low versus COPS2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COPS2→partner) and Y-score (partner→COPS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein localization to kinetochore →	+0.139	+0.857	<.001	<.001	3	16
URINARY_TRACT	Circadian sleep/wake cycle →	+0.180	+0.854	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Protein localization to condensed chromosome →	+0.140	+0.731	.003	.005	3	15
LIVER	Ubiquitin-dependent protein catabolic process via the N-end rule pathway →	+0.094	+0.938	<.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Protein neddylation →	+0.111	+0.994	<.001	<.001	3	13
OVARY	Ribosomal large subunit export from nucleus →	+0.138	+0.881	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,221 associations by consensus.

Protein localization to kinetochore by COPS2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →