COPRS

RNA expression — cross-omics
Cross-omicsRNA → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, COPRS RNA expression is significantly associated with the RNA expression of many other genes, with 17,181 significant associations in total. ACC shows the largest number of these associations.

The most reproducible COPRS-associated genes across cancer lineages are COPS6, NT5C3B, and ANAPC11. Each is linked with COPRS in more than 32 cancer types. Because this analysis shows association rather than direction, both COPRS-to-partner and partner-to-COPRS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COPRS versus COPS6 in SCLC, with a Pearson correlation of 0.45.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COPRS→partner) and Y-score (partner→COPRS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SCLCCOPS6 →+0.737+0.563<.001<.001333
CHOLNT5C3B →+0.955+0.870<.001<.001332
LIHCANAPC11 →+0.884+0.679<.001<.001332
DLBCFIS1 →+0.874+0.712<.001<.001331
DLBCPSMB3 →+0.823+0.686<.001<.001331
ACCPOP7 →+0.829+0.840<.001<.001331
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,181 associations by consensus.

COPRS vs COPS6 — SCLC

Per-sample scatter of COPRS vs COPS6 in SCLC (Pearson r = 0.45).

Explore this scatter interactively →

Exploration