COPRS

Across TCGA patient cohorts, COPRS RNA expression is significantly associated with the protein abundance of many other proteins, with 14,827 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COPRS-associated proteins across cancer lineages are COPRS_S66, C17orf75, and CSE1L. Each is linked with COPRS in more than 5 cancer types. Because this analysis shows association rather than direction, both COPRS-to-partner and partner-to-COPRS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COPRS versus COPRS_S66 in OV, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COPRS→partner) and Y-score (partner→COPRS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	COPRS_S66 →	+0.752	+0.549	<.001	<.001	3	6
BRCA	C17orf75 →	+0.278	+0.451	<.001	<.001	3	5
LSCC	CSE1L →	+0.361	+0.559	<.001	<.001	3	4
BRCA	NPEPPS →	+0.366	+0.465	<.001	<.001	3	4
PDAC	WDR54 →	+0.314	+0.274	.002	.003	3	4
LUAD	ACACA →	+0.329	+0.462	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,827 associations by consensus.

COPRS vs COPRS_S66 — OV

Explore this scatter interactively →