COPRS

Across TCGA patient cohorts, COPRS protein abundance is significantly associated with the RNA expression of many other genes, with 10,074 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COPRS-associated genes across cancer lineages are CPD, PSMD11, and IFT22. Each is linked with COPRS in more than 3 cancer types. Because this analysis shows association rather than direction, both COPRS-to-partner and partner-to-COPRS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COPRS versus CPD in LUAD, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COPRS→partner) and Y-score (partner→COPRS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CPD →	+0.515	+0.201	.002	<.001	3	4
LSCC	PSMD11 →	+0.497	+0.246	<.001	<.001	3	4
LSCC	IFT22 →	+0.646	+0.260	<.001	.002	3	4
LSCC	TUBG1 →	+0.657	+0.248	<.001	<.001	3	4
BRCA	NT5C3B →	+0.590	+0.289	<.001	<.001	3	4
UCEC	BBIP1 →	-0.491	-0.202	.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,074 associations by consensus.

COPRS vs CPD — LUAD

Explore this scatter interactively →