COPG2

Across TCGA pan-cancer cohorts, COPG2 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated COPG2 data layer compared with 26 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher COPG2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated COPG2 expression acts as an unfavorable survival marker, although some lineages such as UCEC and CCRCC show a favorable association.

UCEC, CCRCC, and LUAD are the cancer types where COPG2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	II,III,IV	1.000	0.474	.008	20	view →
CCRCC	DFS	Quartile	All	1.000	0.797	.009	13	view →
LUAD	OS	Quartile	II,III,IV	0.261	0.785	.020	10	view →
PDAC	DFS	Median	All	0.379	0.219	.012	9	view →
LSCC	DFS	Quartile	III,IV	0.491	1.000	.031	4	view →
GBM	OS	Tertile	All	0.654	0.884	.046	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

COPG2–UCEC (DFS)

Open the UCEC breakdown →