COPG2

Across TCGA cell cohorts, COPG2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,611 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible COPG2-associated GO terms across cancer lineages are Positive regulation of isotype switching to IgG isotypes, Mitotic cytokinesis, and Cell division. Each is linked with COPG2 in more than 12 cancer types. Because this analysis shows association rather than direction, both COPG2-to-partner and partner-to-COPG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of isotype switching to IgG isotypes grouped by COPG2-low versus COPG2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COPG2→partner) and Y-score (partner→COPG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of isotype switching to IgG isotypes →	+0.160	+1.362	.001	.006	2	13
LUNG_SCLC	Mitotic cytokinesis →	+0.065	+0.582	.003	.002	3	12
BREAST	Cell division →	+0.088	+1.187	.001	<.001	3	12
LUNG_SCLC	Cytokinesis →	+0.075	+0.781	.002	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Negative regulation of chromosome organization →	+0.082	+0.654	.003	.003	3	11
LUNG_SCLC	Cytoskeleton-dependent cytokinesis →	+0.080	+0.743	.001	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,611 associations by consensus.

Positive regulation of isotype switching to IgG isotypes by COPG2 expression — LIVER

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