COPG1

Across TCGA pan-cancer cohorts, COPG1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated COPG1 data layer compared with 22 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher COPG1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated COPG1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and PDAC show a favorable association.

LSCC, CCRCC, and HNSC are the cancer types where COPG1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Quartile	II,III,IV	0.469	1.000	<.001	39	view →
CCRCC	DFS	Quartile	III,IV	0.362	0.805	.007	26	view →
HNSC	DFS	Median	III,IV	0.896	0.690	.001	24	view →
GBM	DFS	Quartile	All	0.656	0.874	.001	11	view →
PDAC	DFS	Quartile	II,III,IV	0.900	0.667	.018	6	view →
UCEC	DFS	Tertile	All	0.974	0.842	.014	6	view →
LUAD	OS	Median	All	0.903	0.676	.025	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

COPG1–LSCC (OS)

Open the LSCC breakdown →