COPG1

Across TCGA cell cohorts, COPG1 mutation is significantly associated with the RNA expression of many other genes, with 71 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible COPG1-associated genes across cancer lineages are GRIFIN, CCL16, and TCP10L2. Each is linked with COPG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both COPG1-to-partner and partner-to-COPG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GRIFIN grouped by COPG1-low versus COPG1-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COPG1→partner) and Y-score (partner→COPG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	GRIFIN →	+0.080	+4.906	<.001	.006	3	2
URINARY_TRACT	CCL16 →	+0.013	+5.087	<.001	.004	3	2
UPPER_AERODIGESTIVE_TRACT	TCP10L2 →	+0.050	+4.357	<.001	.006	3	2
LUNG_NSCLC_LUAD	OR2B3 →	+0.019	+5.228	<.001	.005	3	2
OESOPHAGUS	ODF1 →	+0.996	+4.906	<.001	.006	3	1
OESOPHAGUS	IZUMO2 →	+0.043	+4.906	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 71 associations by consensus.

GRIFIN by COPG1 expression — OESOPHAGUS

Explore this box plot interactively →