COPB2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, COPB2 mutation is significantly associated with the RNA expression of many other genes, with 5,030 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COPB2-associated genes across cancer lineages are ANKRD33B-AS1, RNA5SP436, and SNORA36A. Each is linked with COPB2 in more than 2 cancer types. Because this analysis shows association rather than direction, both COPB2-to-partner and partner-to-COPB2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COPB2→partner) and Y-score (partner→COPB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
READANKRD33B-AS1 →+0.187+6.681<.001<.00133
SKCMRNA5SP436 →+0.169+4.328<.001.00733
LIHCSNORA36A →+0.270+5.355<.001.00532
READRPL12P5 →+0.135+5.219<.001.00632
READMIR4774 →+0.841+6.257<.001.00132
BLCARPS28P1 →+0.157+3.592<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,030 associations by consensus.

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