COMTD1

Across TCGA patient cohorts, COMTD1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,432 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible COMTD1-associated proteins across cancer lineages are MRPL20, MRPL50, and MTERF3. Each is linked with COMTD1 in more than 4 cancer types. Because this analysis shows association rather than direction, both COMTD1-to-partner and partner-to-COMTD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COMTD1 versus MRPL20 in LSCC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COMTD1→partner) and Y-score (partner→COMTD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MRPL20 →	+0.365	+0.727	<.001	<.001	3	4
LSCC	MRPL50 →	+0.342	+0.795	<.001	<.001	3	4
PDAC	MTERF3 →	+0.432	+0.518	.001	.007	3	4
LUAD	CEP55 →	+0.597	+0.468	<.001	.003	3	4
BRCA	DDX21 →	+0.446	+0.700	<.001	<.001	3	4
LUAD	SUPV3L1 →	+0.330	+0.568	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,432 associations by consensus.

COMTD1 vs MRPL20 — LSCC

Explore this scatter interactively →