COMP

Across TCGA patient cohorts, COMP mutation is significantly associated with the RNA expression of many other genes, with 1,306 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COMP-associated genes across cancer lineages are RN7SKP247, ARF1P1, and MIR649. Each is linked with COMP in more than 2 cancer types. Because this analysis shows association rather than direction, both COMP-to-partner and partner-to-COMP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP247 grouped by COMP-low versus COMP-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COMP→partner) and Y-score (partner→COMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SKP247 →	+0.127	+3.558	<.001	.005	3	3
COAD	ARF1P1 →	+0.259	+3.154	.006	.006	3	3
CESC	MIR649 →	+0.400	+4.705	.001	.003	3	2
BLCA	RNU6-268P →	+0.212	+3.623	<.001	.004	3	2
UCEC	THOP1 →	+0.494	+3.467	.005	.002	3	2
CESC	ANOS2P →	+0.016	+4.539	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,306 associations by consensus.

RN7SKP247 by COMP expression — BLCA

Explore this box plot interactively →