COMMD9

Across TCGA patient cohorts, COMMD9 protein abundance is significantly associated with the protein abundance of many other proteins, with 25,690 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible COMMD9-associated proteins across cancer lineages are SNX5, CAPZA2, and CCDC22. Each is linked with COMMD9 in more than 8 cancer types. Because this analysis shows association rather than direction, both COMMD9-to-partner and partner-to-COMMD9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COMMD9 versus SNX5 in HNSC, with a Pearson correlation of 0.36.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COMMD9→partner) and Y-score (partner→COMMD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SNX5 →	+0.317	+0.301	<.001	<.001	3	9
PDAC	CAPZA2 →	+0.356	+0.356	<.001	<.001	3	9
PDAC	CCDC22 →	+0.235	+0.404	<.001	<.001	3	9
BRCA	VPS26C →	+0.267	+0.307	<.001	<.001	3	8
PDAC	CRYZL1 →	+0.735	+0.518	<.001	<.001	3	8
COAD	NUBP2 →	+0.299	+0.272	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,690 associations by consensus.

COMMD9 vs SNX5 — HNSC

Explore this scatter interactively →