Across TCGA patient cohorts, COMMD6 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,621 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible COMMD6-associated proteins across cancer lineages are UCHL3, CUL4A, and RBM26. Each is linked with COMMD6 in more than 5 cancer types. Because this analysis shows association rather than direction, both COMMD6-to-partner and partner-to-COMMD6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COMMD6→partner) and Y-score (partner→COMMD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	UCHL3 →	+0.470	+0.509	<.001	<.001	3	6
LSCC	CUL4A →	+0.473	+0.686	<.001	<.001	3	5
LSCC	RBM26 →	+0.286	+0.472	<.001	.001	3	5
OV	DIS3 →	+0.418	+0.836	<.001	<.001	3	5
OV	PCID2 →	+0.451	+1.146	<.001	.001	2	6
HNSC	SEC11C →	-1.141	-0.556	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,621 associations by consensus.

Exploration

COMMD6 survival (RNA) · tumor vs normal (RNA) · all COMMD6 data types