Across TCGA patient cohorts, COMMD6 protein abundance is significantly associated with the RNA expression of many other genes, with 7,492 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible COMMD6-associated genes across cancer lineages are MEOX2, AHR, and BHLHE41. Each is linked with COMMD6 in more than 2 cancer types. Because this analysis shows association rather than direction, both COMMD6-to-partner and partner-to-COMMD6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COMMD6→partner) and Y-score (partner→COMMD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	MEOX2 →	+0.780	+0.495	<.001	<.001	3	3
BRCA	AHR →	+0.509	+0.155	.001	.004	3	3
BRCA	BHLHE41 →	+0.796	+0.199	.001	.002	3	3
GBM	TNS3 →	+0.562	+0.214	.004	<.001	3	3
COAD	VSIG4 →	+0.907	+0.267	.003	<.001	3	3
LSCC	GDF6 →	+0.347	+0.162	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,492 associations by consensus.

Exploration

COMMD6 survival (RNA) · tumor vs normal (RNA) · all COMMD6 data types