Across TCGA cell cohorts, COMMD6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,126 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible COMMD6-associated GO terms across cancer lineages are Protein linear polyubiquitination, Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I, and snRNA transcription by RNA polymerase III. Each is linked with COMMD6 in more than 10 cancer types. Because this analysis shows association rather than direction, both COMMD6-to-partner and partner-to-COMMD6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COMMD6→partner) and Y-score (partner→COMMD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein linear polyubiquitination →	-0.120	-0.889	.004	.004	3	11
BONE	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	-0.179	-0.818	<.001	<.001	3	11
BONE	snRNA transcription by RNA polymerase III →	-0.096	-1.047	<.001	<.001	3	11
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	-0.220	-1.117	<.001	<.001	3	11
BONE	Regulation of transcription by RNA polymerase I →	-0.164	-1.107	.001	<.001	3	11
BONE	Regulation of telomerase RNA localization to Cajal body →	-0.118	-0.826	<.001	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,126 associations by consensus.

Exploration

COMMD6 survival (RNA) · tumor vs normal (RNA) · all COMMD6 data types