COMMD4

Across TCGA patient cohorts, COMMD4 protein abundance is significantly associated with the RNA expression of many other genes, with 5,431 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible COMMD4-associated genes across cancer lineages are NTAN1, IFI27L2, and BMP2K. Each is linked with COMMD4 in more than 3 cancer types. Because this analysis shows association rather than direction, both COMMD4-to-partner and partner-to-COMMD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, COMMD4 versus NTAN1 in HNSC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COMMD4→partner) and Y-score (partner→COMMD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NTAN1 →	+0.407	+0.135	<.001	.003	3	4
LUAD	IFI27L2 →	+0.536	+0.104	<.001	.002	3	3
LSCC	BMP2K →	+0.390	+0.119	<.001	.007	3	3
LSCC	ATP6V1B2 →	+0.236	+0.110	.003	<.001	3	3
GBM	VENTX →	+0.846	+0.191	<.001	<.001	3	3
LSCC	TPP1 →	+0.517	+0.119	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,431 associations by consensus.

COMMD4 vs NTAN1 — HNSC

Explore this scatter interactively →