COMMD3

Across TCGA cell cohorts, COMMD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,682 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible COMMD3-associated GO terms across cancer lineages are Positive regulation of immature T cell proliferation, Positive regulation of immature T cell proliferation in thymus, and DAMP biosynthetic process. Each is linked with COMMD3 in more than 12 cancer types. Because this analysis shows association rather than direction, both COMMD3-to-partner and partner-to-COMMD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of immature T cell proliferation grouped by COMMD3-low versus COMMD3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COMMD3→partner) and Y-score (partner→COMMD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of immature T cell proliferation →	+0.465	+0.945	.002	<.001	3	13
SOFT_TISSUE	Positive regulation of immature T cell proliferation in thymus →	+0.465	+0.945	.002	<.001	3	13
STOMACH	DAMP biosynthetic process →	+0.113	+0.644	<.001	<.001	3	8
STOMACH	Purine deoxyribonucleoside monophosphate biosynthetic process →	+0.113	+0.644	<.001	<.001	3	8
BONE	Cellular response to nitrogen levels →	+0.130	+0.530	.003	.002	3	7
BONE	Cellular response to nitrogen starvation →	+0.130	+0.530	.003	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,682 associations by consensus.

Positive regulation of immature T cell proliferation by COMMD3 expression — SOFT_TISSUE

Explore this box plot interactively →