COMMD2

Across TCGA patient cohorts, COMMD2 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COMMD2-associated genes across cancer lineages are B-cells and Neutrophils. Each is linked with COMMD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both COMMD2-to-partner and partner-to-COMMD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B-cells grouped by COMMD2-low versus COMMD2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COMMD2→partner) and Y-score (partner→COMMD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	B-cells →	+0.038	+2.310	.021	.026	3	1
UCEC	Neutrophils →	+0.033	+2.166	<.001	.040	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

B-cells by COMMD2 expression — UCEC

Explore this box plot interactively →