COMMD2

Across TCGA cell cohorts, COMMD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,056 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible COMMD2-associated GO terms across cancer lineages are Positive regulation of cytoplasmic translation, Protein-DNA complex assembly, and Regulation of protein modification by small protein conjugation or removal. Each is linked with COMMD2 in more than 14 cancer types. Because this analysis shows association rather than direction, both COMMD2-to-partner and partner-to-COMMD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cytoplasmic translation grouped by COMMD2-low versus COMMD2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COMMD2→partner) and Y-score (partner→COMMD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of cytoplasmic translation →	+0.129	+0.776	.003	.003	3	15
SOFT_TISSUE	Protein-DNA complex assembly →	+0.056	+0.554	.004	.005	3	15
OVARY	Regulation of protein modification by small protein conjugation or removal →	+0.077	+0.879	<.001	<.001	3	14
OESOPHAGUS	Establishment of mitotic sister chromatid cohesion →	+0.135	+0.754	<.001	.001	3	14
LARGE_INTESTINE	Nuclear envelope organization →	+0.071	+0.768	<.001	<.001	3	13
OVARY	Regulation of post-translational protein modification →	+0.070	+0.973	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,056 associations by consensus.

Positive regulation of cytoplasmic translation by COMMD2 expression — OVARY

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