Across TCGA patient cohorts, COLQ RNA expression is significantly associated with the protein abundance of many other proteins, with 13,527 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible COLQ-associated proteins across cancer lineages are CTNND1_T906, DDAH2, and DDX28. Each is linked with COLQ in more than 5 cancer types. Because this analysis shows association rather than direction, both COLQ-to-partner and partner-to-COLQ results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (COLQ→partner) and Y-score (partner→COLQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CTNND1_T906 →	-0.679	-0.550	<.001	<.001	3	6
LSCC	DDAH2 →	+0.434	+0.608	<.001	<.001	3	6
LSCC	DDX28 →	-0.444	-0.429	<.001	.002	3	5
CCRCC	VCAN →	+1.201	+0.500	<.001	<.001	3	5
PDAC	VIM_S205 →	+0.786	+0.287	<.001	<.001	3	5
BRCA	WDR19 →	+0.287	+0.495	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,527 associations by consensus.

Exploration

COLQ survival (RNA) · tumor vs normal (RNA) · all COLQ data types