COLGALT1

Across TCGA pan-cancer cohorts, COLGALT1 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated COLGALT1 data layer compared with 23 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher COLGALT1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated COLGALT1 expression acts as an unfavorable survival marker.

ACC, SKCM, and GBM are the cancer types where COLGALT1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.046	0.753	<.001	36	view →
SKCM	OS	Median	III,IV	0.216	0.721	.001	12	view →
GBM	OS	Median	All	0.058	0.416	<.001	6	view →
LIHC	OS	Median	All	0.098	0.774	.001	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
PRAD	DFS	Median	All	0.436	0.777	.008	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

COLGALT1–ACC (DFS)

Open the ACC breakdown →