COLGALT1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, COLGALT1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated COLGALT1 data layer compared with 23 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher COLGALT1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated COLGALT1 expression acts as an unfavorable survival marker.

CCRCC, HNSC, and LUAD are the cancer types where COLGALT1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCOSQuartileIII,IV0.3200.923<.00163view →
HNSCDFSMedianIV0.5470.810.00631view →
LUADDFSQuartileAll0.6431.000.0189view →
PDACDFSMedianAll0.3200.497.0049view →
UCECDFSQuartileAll0.7540.961.0158view →
GBMDFSQuartileAll0.2720.512.0156view →
LSCCOSMedianII,III,IV0.7720.891.0262view →
Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

COLGALT1–CCRCC (OS)

Kaplan–Meier survival curve for COLGALT1 mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration