COLGALT1

Across TCGA cell cohorts, COLGALT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,157 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible COLGALT1-associated GO terms across cancer lineages are Multi-pass transmembrane protein insertion into ER membrane, Actin filament depolymerization, and Protein O-linked glycosylation. Each is linked with COLGALT1 in more than 13 cancer types. Because this analysis shows association rather than direction, both COLGALT1-to-partner and partner-to-COLGALT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Multi-pass transmembrane protein insertion into ER membrane grouped by COLGALT1-low versus COLGALT1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (COLGALT1→partner) and Y-score (partner→COLGALT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Multi-pass transmembrane protein insertion into ER membrane →	+0.124	+1.208	.002	<.001	3	14
BONE	Actin filament depolymerization →	+0.205	+1.213	<.001	<.001	3	13
BONE	Protein O-linked glycosylation →	+0.061	+1.009	<.001	.003	2	13
LUNG_NSCLC_LUSC	Membrane bending →	-0.173	-1.395	<.001	<.001	3	11
URINARY_TRACT	Protein depolymerization →	+0.132	+0.862	.001	.004	3	11
BONE	Glycoprotein biosynthetic process →	+0.061	+1.206	<.001	<.001	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,157 associations by consensus.

Multi-pass transmembrane protein insertion into ER membrane by COLGALT1 expression — BONE

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