COLGALT1

Across TCGA cell cohorts, COLGALT1 mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible COLGALT1-associated genes across cancer lineages are OXT, TAS2R8, and C5orf52. Each is linked with COLGALT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both COLGALT1-to-partner and partner-to-COLGALT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OXT grouped by COLGALT1-low versus COLGALT1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COLGALT1→partner) and Y-score (partner→COLGALT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OXT →	+0.048	+3.977	<.001	.001	3	1
SKIN	TAS2R8 →	+0.018	+3.882	<.001	.001	3	1
SKIN	C5orf52 →	+0.041	+4.415	<.001	<.001	3	1
LARGE_INTESTINE	ALDH6A1 →	+1.211	+3.064	<.001	.009	3	1
LARGE_INTESTINE	MFSD14A →	+0.620	+3.064	<.001	.009	3	1
LARGE_INTESTINE	SFTPB →	+0.197	+2.770	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

OXT by COLGALT1 expression — SKIN

Explore this box plot interactively →