COLEC11

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, COLEC11 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated COLEC11 data layer compared with 22 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher COLEC11 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated COLEC11 expression acts as an unfavorable survival marker, although some lineages such as PDAC and CCRCC show a favorable association.

PDAC, LUAD, and CCRCC are the cancer types where COLEC11 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PDACDFSTertileII,III,IV0.8950.645.00523view →
LUADOSMedianAll0.8680.999.01323view →
CCRCCDFSMedianAll0.8590.633.00821view →
LSCCDFSMedianAll0.5240.882.0085view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

COLEC11–PDAC (DFS)

Kaplan–Meier survival curve for COLEC11 mass-spec protein-high vs -low samples in PDAC.

Open the PDAC breakdown →

Exploration