COLEC11

Across TCGA patient cohorts, COLEC11 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. STAD shows the largest number of these associations.

The most reproducible COLEC11-associated genes across cancer lineages are ASNS, eIF4E, and 14-3-3_beta. Each is linked with COLEC11 in more than 2 cancer types. Because this analysis shows association rather than direction, both COLEC11-to-partner and partner-to-COLEC11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by COLEC11-low versus COLEC11-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COLEC11→partner) and Y-score (partner→COLEC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	ASNS →	+0.574	+3.169	.008	.019	3	3
STAD	eIF4E →	+0.190	+3.169	.032	.019	3	2
UCEC	14-3-3_beta →	-0.083	-2.295	.031	.033	3	2
STAD	MYH11 →	-2.496	-3.000	<.001	.033	3	1
STAD	Rictor →	-1.426	-3.169	.003	.019	3	1
STAD	VHL →	+1.064	+3.169	.006	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

ASNS by COLEC11 expression — STAD

Explore this box plot interactively →