Across TCGA patient cohorts, COLEC10 mutation is significantly associated with the RNA expression of many other genes, with 591 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible COLEC10-associated genes across cancer lineages are CPE, RNU6-362P, and MTND6P17. Each is linked with COLEC10 in more than 1 cancer types. Because this analysis shows association rather than direction, both COLEC10-to-partner and partner-to-COLEC10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COLEC10→partner) and Y-score (partner→COLEC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CPE →	-1.072	-3.574	.004	.003	3	2
HNSC	RNU6-362P →	+0.368	+7.954	<.001	.008	3	2
LUSC	MTND6P17 →	+0.103	+7.924	<.001	.008	3	2
SKCM	SMIM4 →	+0.533	+1.880	<.001	.001	3	2
SKCM	KRTAP19-1 →	+1.466	+1.591	.003	.006	3	2
SKCM	BMP6 →	-0.840	-2.565	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 591 associations by consensus.

Exploration

COLEC10 survival (RNA) · tumor vs normal (RNA) · all COLEC10 data types