Across TCGA patient cohorts, COLEC10 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible COLEC10-associated genes across cancer lineages are Bim, MEK1, and VHL. Each is linked with COLEC10 in more than 1 cancer types. Because this analysis shows association rather than direction, both COLEC10-to-partner and partner-to-COLEC10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (COLEC10→partner) and Y-score (partner→COLEC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Bim →	-0.267	-1.874	.010	.049	3	2
UCEC	MEK1 →	+0.419	+3.169	.037	.020	3	1
UCEC	VHL →	-0.858	-3.169	.021	.019	3	1
SKCM	PRAS40_pT246 →	+0.126	+2.321	.042	.032	3	1
SKCM	Shc_pY317 →	-0.153	-1.567	.038	.035	3	1
SKCM	Axl →	-0.580	-2.985	.006	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

COLEC10 survival (RNA) · tumor vs normal (RNA) · all COLEC10 data types